An interesting way to connect the TNTL with a Line 6 product, is to put the Live in the loop of the Pod.
That way, you can have effects BEFORE and AFTER the Live. So you can put the stereo effects after the miking, that is very interesting.
Be sue to bypass all the cabinet simulation and power amp simulation in the POD (if it's possible).
I have no idea what the latency will be, though...