Edit:
Might as well put an explanation of the setup here because I think it's kind of nifty and was planned quite carefully.
Main point, I mostly use the monitors and IRs.
Guitar goes to tuner, then a buffered isolated splitter, output A goes onto the main board, and B feeds the 2 noise gates which are 3CM'd to the loops of the amps.
At the end of the board, the signal gets split to a buffered isolated AB/Y, then into the mimiq.
Each output of the Mimiq feeds one amp.
Amps make sound. Loadboxes feed 2 channels of my interface.
The amps both have lineouts and feed the stereo ins of the Core.
The Core has the capability to setup a pseudo 2 stereo channel line mixer internally, and cut all dry signal.
On each side there's different delays (currently tap tempo'd at quarter and 8th intervals) and detune/micropitchshift.
100% wet, and then the stereo outs on the core feed 2 more interface channels.
IRs via Wall of Sound and Reverb is done in Reaper, but I may setup a way of doing the reverb physically at some point.
WDDW