Regardless, the answer is fairly similar I suppose. At the end of the day you will likely just sequence midi and run a plugin over it to make your sounds. You can use EZ Drummer, Superior Drummer, Steven Slate Drums if you want a VST style kit. They are versatile and have downloadable drum libraries that are good. Alternatively, you can use Kontact and download drum samples from different companies (STL Tones, Bogren, Joey Sturgis) that are usually more like one trick ponies (fewer velocity options and tweakability in ways), but are usually great at giving pro sounding results with minimal fuss and are more or less ready to go. I used to use VSTs a lot more but have been getting better results quicker using Kontact to host samples.
Just use the DI on your Focusrite for direct recording of bass and guitar and use an amp sims with some good IRs. Bogren or Ownhammer make really nice ones. If you want to direct track your amp, you can get a load box for the head and track the head and match it with an IR. Personally, I like the Boss Waza for workflow and simplicity and you can match it with an IR in the hardware. That's just a workflow preference. I believe others have posted (VESmedic? I think) have had good experiences with the Driftwood box--I'm sure that one rocks too. Overall, a few pieces of software and a load box (if you want to track your amp and not use a sim) are really all you need.
