Yes, you can do it easily by bypassing the Axe's power amp sims and using the TL's (probably best to put the TL in the Axe's FX Loop).
I've done this with the Axe Ultra and preferred the Two Notes tube power amps sims personally, but it's subjective etc.
Ultimately I prefer real tube preamps with the Two Note's tube power amp sims and normally use my Axe Ultra for FX (great FX box!).