That would be my choice, but I know that different guys have different gear needs. Some guys for example really prefer new amps, and that's cool. I like Mesa & want them to stay in business so they need to sell new amps! Some guys really prefer the more modern compressed thing, and that's cool too- V and newer it is. Since the OP wanted to compare those two specific choices I thought it better to answer the question rather than throwing rocks in the pool. That being said..
If I needed a Mark for general gigging, I could be happy with a loop modded IIB, III, IV or JP2C.
If I needed a Mark for recording, I could be happy with a IIC+ or IV.
If I needed a Mark for home play, I could be happy with any of them except the 90w V.
The VII does have a lot of really great things about it, and a couple things that for me personally were deal breakers- but, these are things that if you weren't A/Bing with the OGs at high volume you would never know & could be totally happy. Or, maybe your needs are different & what I experienced wouldn't matter to you. There are hairs to split of course, and YMMV.