I can agree with Guillaume on this area!
I recently had to switch to a more...how do you say..."back friendly" setup but I still needed a monitor on stage. I picked up a Line6 PodHD Pro and Line6's amp models are spot on great, BUT their cabinet emulations, quite frankly, stink. So, I had the idea to put the HDPRO and my Live into the same rack and I use the cab emulations on the live with the amp modelling on the PodHD PRO. It sounds even better than the Kemper that I previously had. Very full, clear and crisp.
I run this through a Mackie HD1221 for on stage monitoring which I got for an amazing price. I'm also playing with a Traynor K4 keyboard amp that is FRFR. The Mackie is a beautifully clear system with fantastic bottom end and clarity. I don't miss my 4x12 one bit. While I think the CLR is a great product, at $1000, I'm not paying only to get an email back stating that I have to wait 4 months to get it. That to me is a poor business model.
If I need to run direct, I can simply take the output from the live into the PA or monitor from my Mackie. I only wish the Live had 2 outputs for this reason. It would make it the perfect product. I can still run both at the same time but I would then need to use two amps in the Line6 settings and run one side through the line6 emulations and the other side into my Torpedo and into my Mackie. Either way it is doable.