I actually run both. I have my Timefactor, Space, Ibanez Lo Fi and Maxon OD808 all in my rack running through an Axess Electronics GRX4, and on my board I have my Axess Electronics FX1, BS2, Korg Pitchblack, TC Corona Chorus, MXR EVH 90, MXR Uni-Vibe, Digitech Whammy V all running through another GRX4. I thought about going all rack, but enjoy having the modulation pedals on the floor for tweaking on the fly.