4 tubes slots = 4 tubes IMO.
Not sure why you would want to do this when you have a Master Volume. Of course you can choose to run only 2 tubes and will get less power. Not equal to 1/2 necessarily, however it will drop the wattage.
Many have tried this, including me (never on a Diezel though). The question is, "will it sound the same as if you had all 4 tubes in". The answer is generally, no. So, that's why I would agree with Joni here, buy 4.
You can always pull 2 after you rebias and try the options. If you only buy 2 you will not be abl to try both ways and won't know the differences or whether you would prefer all 4 in.
You might ask Peter if there are any negative repercussions to trying this with your amp before you take ANYONE else's word for it.
Happy experimenting...