Let me guess….Hendrix is #1.
To be honest, that I don't mind and actually agree with. He was the biggest 'change' in rock guitar.
If you look at guitarists who are both great players AND who've had a lasting impact on not only music, but also associated subcultures and other guitarists, Hendrix should be #1, EVH #2 and #3 is highly, highly, HIGHLY debatable... (just spitballing, it could be Reinhardt, De Lucia, Schenker, Rhoads, Clapton, Segovia, Page, Knopfler, Atkins, Blackmore, Johnson (Robert, not Ellen Degeneres....) etc.)
To me there's a clear difference between 'who's the most accomplished guitarist who has mastered the instrument' vs. 'who has had the most impact on the course and shape of music as a whole, even though they might be not as 'virtuoso'?
Take Steve Vai vs. Ace Frehley for instance. Objectively, Vai can do 'more' on and with a guitar. But did he inspire as much young kids to pick up the guitar in the first place? And sure, Frehley was becoming big in a time when guitar and rock music was big, so he had that benefit.
Or take Chuck Berry...not a 'master of the guitar' by any means, but the man almost single-handedly defined rock 'n roll!
(Yes, I'm very aware of Ike Turner, Bill Haley, etc.)
These days we have people gushing about Tim Henson. I'm sure he's great, but a Blackmore or Schenker had way more impact on rock/metal music and guitar playing.
Just my 2cts.