Severe drop in gain leads me to think there's a bad preamp tube. Saturation shouldn't be an issue with the Mark V. Also check your presence control. Too much can really thin out the sound. I don't run mine much above 11:00.
Ultimately if it's not something in the preamp you may want to consider another option. 5150/6505 series amps have a lot of gain on tap (like anything above 12 o'clock is unnecessary). If you're not concerned with cleans or more moderate crunch, just get a regular 5150/6505 and run it as a single channel amp. It's worth noting that that same amp being run in crunch mode and boosted, sounds heinous. ENGL might be an option too, although there's a bit more compression to the ENGL sound than a Peavey. I like ENGLs but that's just part of their tone. I can't comment on the Uberschall as I've never played one, but I've heard wonderful things.
Also, depending on the passives in the Dean, that may also explain the drop in volume. Nevermind I see it's a L-500XL. My apologies.