After many years of flipping amps, and tone hunting, I found my tonal salvation in a VHT CL100 w/ EQ. Its just about everything I want in an amp. It has soaring high gain, that's soooo articulate. It also feels like no other amp. The CL has 2 channels. I use the green channel as my gain channel. I always use it with the EQ and the sliders typically are in a V shape. The red channel is set up as my clean. I run it with the gain very low and the master very high. I switch the EQ on and off depending on what tone I'm going for. I've been using 2 EHX pdeals with the clean, a Soul Food and Lumberjack to provide just a hint of grainy overdrive/ fuzz for a classic rock kind of vibe. I also play around with the poweramp feel. I can make it tighter feeling, or go more for a marshall-type feel.
Ive hads many amps in my time, but my VHT really is the best amp I've ever played. I'd like to eventually get a Deliverance 60 and Memphis.
Yes, the EQ does matter, so get a VHT/ Fryette with the EQ, or throw one in the loop. The FX loops are also the best in the business.
As for what model you should get... well, all of Steve's designs are based around the Pitbull architecture-
If you're a set it and forget it, one channel guy, who plays around with your volume knob, who wants "bowl you over power" I'd go deliverance.
If you're into classic rock/ jazz/surf/ 70's hard rock, I'd go memphis. There's also the option of the old VHT Pitbull 45 combo
If you want 2 insanely versatile channels, that can do clean through metal on either channel, I'd do a CL100.
If you want 2 and 1/2 channels, a dedicated Clean, gain 1 and higher gain 2 (shared EQ), I'd get a CLX. Or if modern metal/ prog is more your cup of tea, I'd check out an UL.
If you want lots of tonal options and a very dry amp, your ticket is a SIG:X
hope this helps. Peace~