Hopefully Todd (Victim5150) will jump in here. He has used so much stuff for his gigs and can give great info
I now use an FM9, previously AX8 and Axe III. Very simply, FM9 + one EV1 expression for wah. One mono out to personal FRFR monitor over which I have complete control, one mono out to FOH which also comes back in stage monitors (sometimes I dispense with personal FRFR and just piggyback on the stage monitor depending on what gear the sound guy brings). WIth my Mono dual guitar case/bag I can load in out in one trip. This is for a typical bar/private event type band.
Whether Kemper, VST amp/cab sims, or my Suhr Pt-15IR, I prefer to run into my studio monitors, I play through them almost exclusively and always have, regardless of whether it was my old KRK Rokit 5s, or my current Neumann KH80 DSP/KH750 setup, monitors have been my preferred way to play guitar since I was able to.