I've been using a 10'' yamaha frfr with great results. Honestly, I do not miss my old tube amps, not a single one and i've had a bunch over the years.
Again the problem I see with most folks is that they are trying to replicate the 'in room' sound. You can achieve that with a profile that has a combination of mics to create that full thump in your chest. Also running profiles through poweramps and real cabs requires you to find a profile that allows you to work with just the preamp section. Not a full 'amp' into another poweramp situation.
BTW...Have any of you who use tube amps heard yourself through a regular PA at the local venue?

Or have any of you really just mic'd up your amps/cabs and did you listen to what they really sound like mic'd up? Kemper, axe, helix, pod, QC these are all tools for live use/recording where most had simply been developed to cut cost for touring bands and gigging musicians.
If we assume that kemper and the likes are maybe 95-98% there depending on the profile but we're getting a consistent 95-98% each time we play live then i am absolutely fine losing those couple of %s. Because unless you have your own tech - with live amps you will just sound different each night due to mic placement. Also 99% of the audience can't hear shit so....why bother