Had one in my Suhr S2, which is Alder with a Maple neck...thus far, it's been one of my three favorite PAF-type pups (along with MC 2nd degree and Arcane Brownbucker). Only reason I took it out is that I'm just interested in trying different ones. The Thornbucker has an A4 magnet also, which takes a little shrill off the high end.
Like any pickup though, it really can be a different experience depending on the guitar (wood, neck, etc.)