I currently have a JVM410HJS. It is a fantastic amp both sound a feature-wise. I do miss some of the tightness with other brands I have used but it does the job remarkably well. I run a Maxxon VOP-9 in front of it to help tighten things up a bit more. I don't love carrying it around all of the time when I play. I'm not quite ready to move to Bias as my main rig but I use it for jamming around the house and having some fun.
That being said, I am actively looking once again at a Kemper but this time in the rack version. I had the previous lunch box version for a year and I did really like it. I just couldn't jive with it live at the time through a power amp and cab and it was missing a few key pieces (Librarian for organizing, a working footswitch solution, and the performance mode). All of those things have been answered and thus, I think that I can move back to it. The solution for me would be very, very workable with the FRFR that I'm looking at. It sounds damn close as well and is easy to use. Don't be fooled thinking it isn't good enough. There are plenty of recordings and pro players using it live now to justify it. The Axe II is the same. Many, many folks using those as well.
Still....having some second thoughts about selling my Marshall. I really do like it.
Best of luck with your choice.