My old setup was a MIDI controller with a TC G-Major running all of my effects. THe front end pedals are still the same. I was getting some adverse tone effects with the G-Major. Mainly, it attenuated some highs, and I was getting some note "smear."
My main complaint with the Nova System is that when you press one of the preset buttons, it doesn't change the preset or my amp channel (handled via MIDI) until you release the switch. So you have to anticipate the preset change slightly. The other issue that I have is that there is a slight dead space whcn changing presets. Both of these things I believe could be resolved with some progrming on TC's part.