There's an issue and I don't think it's your guitars. At least I wouldn't start there.
I'm hearing some nasty highs on what could be a cymbal or hi-hat. It's so bad that it's coming in as noise.
The guitar seems to sound pretty good and the playing was shred-a-licious.
Here's what I'd do:
1-Turn off processing (eq, compression etc)
2-Start with the drums, lower everything else to -infinity on the faders
3-Get the entire drums kit to -18dbfs max. I know it sounds low, but believe me, gain-staging works wonders.
4-Bring in the bass (I'm not sure it exists in the mix the way it currently is). Balance the bass with kick drum. Pan it straight down the middle or close to it.
5-Bring in the rhythm guitars. I like to pan them hard right and hard left if you have 2 tracks. If you only have one, experiment with panning it right.
6-Bring in the lead. Pan it to the left but keep it close to the middle. Often times, you won't need to reduce the level. Simply panning it off-center will help it sit in the mix better.
Before you do anything else fx-wise make sure the mix sounds pretty good with nothing but panning and levels. The next step is to look for instruments competing for the same sonic space and using EQ to carve out a some space.
God! I can go on all day like this. Give that a whirl.