I had the same experience with Bruce Zinky and his Eminence speakers.
The Mofo is an AC-15 clean and '59 BF Bassman modded front end with a 550v Sovtek MiG-50/60 PT/4K OT and his assorted gravy, mainly the MOFO channel being about the same as the Fender Tone Master.
Bruce also likes Sovtek pre's, LPS, and Sovtek Wafer Base 5881's.
He voiced the tone stack with an early 50's Esquire, likely with a really weak alnico II pickup.
It's too bassy and simultaneously paint-peelingly harsh/bright stock. I mean, "God damn, what was he thinking?" level.
Plug a Strat with antiquity Texas hots and it's fucking Keith Richards. Like, shut up and bang out "Start Me Up" and prepare to get laid later Keef toanz. All the shenanigans is for getting those perfect, weak A2 mag tones.
Wanna play rock/do your own thing with it? Experiment for 17 years, get new preamp tubes, trannies, and finally Mesa Vintage 30's, and well, you're happy like me.
Otherwise, yeah change the speaker or play A2 pickups.