Actually the setting of the ground switch could cause some not so obvious issues under just the right circumstances. The switch on the M4 disconnects the circuit ground from the chassis. This makes it so that when you put it in a rack and it gets chassis ground from the rack rails, you can separate the circuit (audio) ground from the common rack (power ground) to prevent that ground loop. If you were to not have the chassis grounded to the rails and the third prong (ground pin) on the AC plug were not grounded properly, the chassis would not be grounded and would not act as a proper shield. This could surely wreak all sorts of havoc, especially with high gain modules. This would tell you it should never be necessary to list the third prong ground (safety) on the AC cord for any reason on the M4..