What I enjoyed was running the powerhead mono output center 'dry' without cabinet simulation, and the effected signal to my mixer/monitors. As I mentioned before, a 2290 in the Kemper stereo loop defies all!
What ruins the fun for me, is that I only use one gain tone and one clean tone... Having hundreds of virtual rigs messed with my ears, so I would generally lock into a couple of rigs, and that was it. I uploaded a couple of profiles; and as good as they came out, I still preferred the sound of the actual rigs. I think the Kemper (and other systems) are great for sound engineers, and players who travel a lot doing freelance, covers, seminars, etc...
That being said... I must have another Kemper.