Probably not the answer most guys would want since it’s stupidly priced now, but of the 160+ boosts I’ve been through easily a Klon centaur (especially with your amps), but some of the klones like the Decibelics are solid alternatives and with your Mesas in particular my other favorites are the recent Tamura modded Tubescreamers and Fortin modded ones. The Tamura ones also are low noise as a nice bonus. The Fortin TS can be a bit much sometimes, but I love it
My vintage TC integrated pre is quite good too, the recent made copies like the Dirty Tree or Fortin 33 I didn’t like as they sounded too filtered and sterile. The vintage Furman PQ3’s are incredible but super noisy and expensive. Everything else I’ve tried for this criteria need not exist as far as I’m concerned
TL;DR I’d say check out the Tamura & Fortin Tubescreamers and some of the good Klones
EDIT: there are a few other excellent vintage PQ units, but they are also very noisy and expensive like the Audioarts 4100 and Intersound units