Never played a IIC+ so take this with a grain of salt. If you love the lead channel on the V and can live without channel 2 get rid of it and get a III or IV. Imo the lead sounds way better on these but channel 2 pretty much sucks on both of them with not much gain and the cleans are not as good as the V. Not that you were even asking about buying a new amp but you can save some money getting these cheaper and there are several IIIs in the classifieds here right now in excellent condition for around $800 dollars. Killer amp, right now my favorite in my collection (uberschall blue, chupacabra, mark V, mark III). Wishin I had never got rid of the mark IV for the V. This stuff is all subjective though. I'm gonna get rid of all the rest soon and keep the mark III, its supposedly close to the IIC+ but who knows.