If you already have a bunch of guitars with humbuckers in them, it is fun to have one "real" strat around for that sound with a great neck. It's at least worth a consideration. I have an old Jackson strat that came with 3 singles in it. It came with the Duncan blade pickups in it, which sounded fine but I already have a bunch of super strats with full humbuckers. I ended up putting a set of Barden's in it and just use it as my strat: pointy headstock, real Floyd, and all. Sounds great. Plays like butter.
If you do swap pickguards, it's just screws to take them off and swap them, though you need to solder/desolder wiring to the jack and bridge (or snip them) as part of the process. Make sure to track one down that has screw holes that line up with the Charvel holes. You don't want to add new holes to the pickguard or definitely not the body.