When if it’s more or less an apples to apples comparison maybe string through is better, but my 4 older Gibson’s are the best sounding and most resonant guitars I’ve owned and obviously not string through. I guess also there’s that great sounding Charvel I just got that’s Floyd Rose (no string through). Almost everything else I have though is string through
I think string through is possibly better with all else being equal, but other factors may matter more to the overall package