I mean short of direct American military involvement this is probably the next best option as the US already provides weapons to Isreal or provides weapons to Ukraine as well to defend it self.
If it was done with American oversight but not direct involvement, I dont see an issue with this but it still stands......
Your going to need more than one MOAB or a couple possibly to destroy the Fordo facility......... your going to have to be sure the Fordo facility is 100% destroyed and sure thats the only place they enrich plutonium/uranium...... if the Israelis do it with American oversight and not direct involvement I imagine all Americans ask is that they simply destroy the facilities with minimal collotareral damage.
Killing the Ayatollah or other military excursions beyond that would not be advised IMO.......
But in either case how long would it really push them back and when they aquire a nuke...... the situation will be made that much worse given what Israel prepares and is willing to do.
I mean its a tough one and I think its a viable option but I still feel the best option is to find a diplomatic approach and a peaceful long term solution vs bombing Iran. The best option and solution is diplomacy IMO with or without direct American military involvement.