I have a set in a PRS singlecut trem satin. Replaced the stock PRS 6 pickups. Lowered the overall output but added a lot of definition to the sound of the instrument and added a bit of mid body that was missing. The singlecut trem is basically a CU22 trem with a single cutaway, the pronounced mids definitely helped this guitar. The overall spectrum response is very pleasing particularly with high gain amps where a thinner, maple-topped guitar can get a little brittle sounding. The versatility and dynamic range of the pickups is amazing, highly responsive to small changes in your picking. I will add a vote to the neck being the velvetiest/juciest neck pickup I've tried. They do well clean to all out distortion because they are only slightly hotter than a PAF or PRS 57/08's. If you have a slightly thinner sounding mahogany guitar, or a guitar with hot pickups that smear the character of the instrument the BDs will do well.