easily!
Axefx Ultra > Fryette 2/90/2 > Fryette fatbottom 4x12
I've had this setup for about 9 months now. All i really need to do is swap out my GCP for an
MFC101 so i can get rid of my floor tuner and swap out my Shure SLX wireless for a G90 and I'll be totally set.
This setup has proven to be 100% reliable at over 70 shows, It's compact and very clean with few connections, it has a fast pack up/pack down time and absolutely nails all the tones I need with little fuss. I only use one side of the 2/90/2 so if i have a tube failure on one of the channels i can easily just switch it over to the other side.
Might be a bit too bare-bones for some folk on this forum but for my application I really couldn't be happier with this rig.
Other guitarist in my band has just about the same setup but he uses an ENGL pro cab, The different cabs complement each other perfectly and both sound distinct whilst blending very well together. Our stage sound has been totally transformed and these rigs have proven to sound ridiculously good and consistent night in, night out.
EDIT: here's a crappy picture i took when i first got it, pedals are mounted on a Pedaltrain 2 with a Fueltank JR PSU and I have since swapped the rocktron utopia expression for a mission SP-1. I'll get a better snap of it shortly. As for guitars I am mostly using ibanez's for my band, namely an RGT320Q & JC-CM1 both loaded with bareknuckle C-pigs (the JC also has an irish tour single). I have to BRJ customs on order, both jekylls and the first should arrive within the fortnight (been waiting for 11 damn moths for the first one!)